Preclinical evaluation of a TEX101 protein ELISA test for the differential diagnosis of male infertility

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Preclinical evaluation of a TEX101 protein ELISA test for the differential diagnosis of male infertility

BACKGROUND TEX101 is a cell membrane protein exclusively expressed by testicular germ cells and shed into seminal plasma. We previously verified human TEX101 as a biomarker for the differential diagnosis of azoospermia, and developed a first-of-its-kind TEX101 ELISA. To demonstrate the clinical utility of TEX101, in this work we aimed at evaluating ELISA performance in a large population of fer...

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ژورنال

عنوان ژورنال: BMC Medicine

سال: 2017

ISSN: 1741-7015

DOI: 10.1186/s12916-017-0817-5